This book is OFF THE HOOK !
Wanna REALLY dissect a running application ?
IDA Pro is THE tool of choice for disassembly and the crackers choice because of it's raw power.
Whether you need to solve a tough runtime defect or examine your application security from teh inside out IDA Pro is a great tool and this book is THE guide for coming up to speed.
From the book description ....
Identify known library routines, so you can focus your analysis on other areas of the code Extend IDA to support new processors and filetypes, making disassembly possible for new or obscure architectures Explore popular plug-ins that make writing IDA scripts easier, allow collaborative reverse engineering, and much more Utilize IDA’s built-in debugger to tackle obfuscated code that would defeat a stand-alone disassembler
Download Chapter 12: "Library Recognition Using FLIRT Signatures"
http://www.nostarch.com/idapro.htm